Anti-Lewis antibody |Pregnancy Terms | Pregnancy Glossary

A protein made by the immune system that binds to molecules called the Lewis antigens, Le a and Le b. Lewis antigens are not made by the red blood cell, but are antigens present in body fluids and secretions that have been adsorbed onto the surface of the red blood cell. Lewis antigens are found in very low levels on the fetal red cells. Most Lewis antibodies are of the IgM type and do not cross the placenta. Lewis blood group antibodies are not known to cause hemolytic disease of the newborn.

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